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COVID-19 infections in U.S. may be much higher, new estimates show: But even moderate interventions can help reduce spread, according to study — ScienceDaily

By March 1, 2020, between 1,043 and 9,484 people in the U.S. may have already been infected by the COVID-19 coronavirus, far more than the number that had been publicly reported, according to a new Cedars-Sinai study. “This suggests that the opportunity window to contain the epidemic of COVID-19 in its early stage is closing,” […]

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New study on COVID-19 estimates 5.1 days for incubation period — ScienceDaily

An analysis of publicly available data on infections from the new coronavirus, SARS-CoV-2, that causes the respiratory illness COVID-19 yielded an estimate of 5.1 days for the median disease incubation period, according to a new study led by researchers at Johns Hopkins Bloomberg School of Public Health. This median time from exposure to onset of […]

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Antibiotics discovered that kill bacteria in a new way — ScienceDaily

A new group of antibiotics with a unique approach to attacking bacteria has been discovered, making it a promising clinical candidate in the fight against antimicrobial resistance. The newly-found corbomycin and the lesser-known complestatin have a never-before-seen way to kill bacteria, which is achieved by blocking the function of the bacterial cell wall. The discovery […]

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Artificial intelligence yields new antibiotic: A deep-learning model identifies a powerful new drug that can kill many species of antibiotic-resistant bacteria — ScienceDaily

Using a machine-learning algorithm, MIT researchers have identified a powerful new antibiotic compound. In laboratory tests, the drug killed many of the world’s most problematic disease-causing bacteria, including some strains that are resistant to all known antibiotics. It also cleared infections in two different mouse models. The computer model, which can screen more than a […]

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Drug meant for Ebola may also work against coronaviruses: Understanding how drugs work is an important step in developing new treatments for COVID-19 — ScienceDaily

A group of University of Alberta researchers who have discovered why the drug remdesivir is effective in treating the coronaviruses that cause Middle East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS) expect it might also be effective for treating patients infected with the new COVID-19 strain. “Even if you know a drug works, […]

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Preventing spread of SARS coronavirus-2 in humans: Infection researchers identify potential drug — ScienceDaily

Several coronaviruses circulate worldwide and constantly infect humans, which normally caused only mild respiratory disease. Currently, however, we are witnessing a worldwide spread of a new coronavirus with more than 90,000 confirmed cases and over 3,000 deaths. The new virus has been named SARS coronavirus-2 and has been transmitted from animals to humans. It causes […]

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New way to test for drug resistant infections: Scientists have developed a method to test whether an infection is resistant to common antibiotics — ScienceDaily

Scientists have developed a method to test whether an infection is resistant to common antibiotics. Beta-lactam antibiotics (such as penicillin) are one of the most important classes of antibiotics, but resistance to them has grown to such an extent that doctors often avoid prescribing them in favour of stronger drugs. Scientists from the University of […]

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Deadly ‘superbugs’ destroyed by molecular drills — ScienceDaily

Molecular drills have gained the ability to target and destroy deadly bacteria that have evolved resistance to nearly all antibiotics. In some cases, the drills make the antibiotics effective once again. Researchers at Rice University, Texas A&M University, Biola University and Durham (U.K.) University showed that motorized molecules developed in the Rice lab of chemist […]

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Japan approves ViiV’s two drug regimen Dovato for HIV

ViiV Healthcare’s human immunodeficiency virus (HIV) drug Dovato (dolutegravir 50mg/lamivudine 300mg) has been approved by the Japanese Ministry of Health, Labour and Welfare (MHLW). Dovato is a once-daily, single pill, two-drug regimen approved to treat adults and adolescents aged over 12 with HIV type 1 (HIV-1) infection who weigh more than 40kg. The drug is […]

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Novo Nordisk secures FDA expanded indication for Ozempic

The US Food and Drug Administration (FDA) has approved a new indication for Novo Nordisk’s Ozempic (semaglutide). The once-weekly injection is now indicated to reduce the risk of major adverse cardiovascular events (MACE), such as non-fatal heart attack or stroke and cardiovascular death, in adults with type 2 diabetes and established cardiovascular disease (CVD). FDA […]

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