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Possible cause for Alzheimer’s and traumatic brain injury discovered — ScienceDaily

Rutgers researchers have discovered a new mechanism that may contribute to Alzheimer’s disease and traumatic brain injury. They now hope to launch a clinical trial to test the treatment in humans. What causes Alzheimer’s is unknown, but a popular theory suggests a protein known as amyloid-beta slowly builds up a plaque in the brains of […]

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Vast leukemia dataset could help researchers match therapies to patients — ScienceDaily

After years of work, researchers are releasing a massive dataset detailing the molecular makeup of tumor cells from more than 500 patients with an aggressive blood cancer called acute myeloid leukemia (AML). The dataset includes how hundreds of individual patients’ cells responded to a broad panel of drugs in laboratory screens. It is the largest […]

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Drug cocktail almost doubles lifespan of worms — ScienceDaily

A team of researchers led by Principal Investigator Dr Jan Gruber from Yale-NUS College has discovered a combination of pharmaceutical drugs that not only increases healthy lifespan in the microscopic worm Caenorhabditis elegans (C. elegans), but also delays the rate of ageing in them, a finding that could someday mean longer, healthier lives for humans. The study, […]

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Half a million tests and many mosquitoes later, new buzz about a malaria prevention drug — ScienceDaily

Most malaria drugs are designed to reduce symptoms after infection. They work by blocking replication of the disease-causing parasites in human blood, but they don’t prevent infection or transmission via mosquitoes. What’s worse, the malaria parasite is developing resistance to existing drugs. “In many ways, the search for new malaria drugs has been a search […]

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DelSiTech partners with Innovare to create long-acting HIV drug

Finnish drug delivery company DelSiTech has signed a licensing agreement with Mexico-based pharmaceutical group Innovare to develop a long-acting human immunodeficiency virus (HIV) therapy. Innovare will leverage DelSiTech’s Silica Matrix drug delivery platform, which controls the release of the drug and can thermostabilise products for many years, for its peptide membrane fusion inhibitor that targets […]

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8,000 new antibiotic combinations are surprisingly effective: Grouping 4 or 5 existing medications could help slow antibiotic-resistant bacteria — ScienceDaily

“We shouldn’t limit ourselves to just single drugs or two-drug combinations in our medical toolbox,” said Pamela Yeh (left), with Elif Tekin. Credit: Reed Hutchinson/UCLA Scientists have traditionally believed that combining more than two drugs to fight harmful bacteria would yield diminishing returns. The prevailing theory is that that the incremental benefits of combining three […]

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Sugar pills relieve pain for chronic pain patients: Placebo benefits can be predicted by brain anatomy and psychological traits — ScienceDaily

Doctors should consider treating chronic pain patients with sugar pills, new research suggests. Placebo pills relieve pain as effectively as drugs for half of chronic pain patients. Credit: © 18percentgrey / Fotolia Someday doctors may prescribe sugar pills for certain chronic pain patients based on their brain anatomy and psychology. And the pills will reduce […]

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New means to fight ‘un-killable’ bacteria in healthcare settings: Canadian scientists identify new cellular target to weaken P. aeruginosa — a severe threat to patients with cystic fibrosis — ScienceDaily

Dr. Dao Nguyen looking at Pseudomonas aeruginosa that has been listed among the “nightmare bacteria” by the Centers for Disease Control and Prevention (CDC) in the United States, with an estimated 51,000 healthcare-associated infections each year resulting in around 400 deaths. P. aeruginosa is a common cause of healthcare-associated infections such as pneumonia, bloodstream or urinary tract infections, and […]

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Possible cause for Alzheimer’s and traumatic brain injury discovered — ScienceDaily

Alzheimer’s definition (stock image). Credit: © Feng Yu / Fotolia Rutgers researchers have discovered a new mechanism that may contribute to Alzheimer’s disease and traumatic brain injury. They now hope to launch a clinical trial to test the treatment in humans. What causes Alzheimer’s is unknown, but a popular theory suggests a protein known as […]

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Gene and cell therapies: making manufacturing work – Pharmaceutical Technology

Gene and cell therapies are two of the fastest emerging areas of medicine. Comprising techniques such as gene editing and next-generation immunotherapy, they could treat – or even cure – a broad range of previously untreatable diseases. To understand their potential, we only need think of the examples that have already been approved. Kymriah, a […]

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