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Scientists can now manipulate brain cells using smartphone — ScienceDaily

A team of scientists in Korea and the United States have invented a device that can control neural circuits using a tiny brain implant controlled by a smartphone. Researchers, publishing in Nature Biomedical Engineering, believe the device can speed up efforts to uncover brain diseases such as Parkinson’s, Alzheimer’s, addiction, depression, and pain. The device, using […]

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What can be done to make pharmaceutical machines run for longer?

Pharmaceutical machines don’t come cheap. But failing to maintain them can prove even more costly and ruin any chance of a return on investment. There are two key ways to make production machines run longer. Firstly, they need to be properly maintained. Secondly, the people operating them need to be doing so correctly. Otherwise, breakdowns […]

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US researchers launch neurohub for brain disease therapies

US researchers have launched a research network, Weill Neurohub, to develop treatments for brain and nervous system diseases and disorders. Weill Neurohub will involve neuroscientists and researchers from the University of California, Berkeley (UC Berkeley), the University of California, San Francisco (UC San Francisco) and the University of Washington (UW). The hub is supported by […]

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FDA grants priority review to tumour drug selumetinib

FDA previously granted breakthrough therapy and orphan drug designations to selumetinib. Credit: The US Food and Drug Administration/Michael J. Ermarth. The US Food and Drug Administration (FDA) has awarded priority review status for AstraZeneca and MSD (Merck)’s selumetinib to treat neurofibromatosis type 1 (NF1) and symptomatic, inoperable plexiform neurofibromas (PNs) in children. If approved, selumetinib […]

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Beigene receives its first FDA approval for a MCL drug

Chinese-headquartered Beigene has announced the US Food and Drug Administration (FDA) has approved Brukinsa (zanubrutinib) to treat patients with relapsed or refractory mantle cell lymphoma (MCL), making this the first Beigene-discovered product to gain FDA approval. The accelerated approval was based upon overall response rate (ORR) results from two single-arm trial; ORR data was assessed […]

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Liquid biopsies reveal genetic alterations linked to cancer drug resistance — ScienceDaily

Many patients see their tumors shrink in response to a drug, only to have them come back with a vengeance as they evolve to fend off the treatment. Oncologists want to be able to quickly detect cancer drug resistance as it emerges in their patients and identify another drug the tumors will still respond to. […]

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Cancer drugs don’t always work as intended, researchers warn — ScienceDaily

Scientists at Cold Spring Harbor Laboratory (CSHL) have identified 10 cancer drugs currently in clinical trials that do not work how clinicians thought they would. In identifying what went wrong, experts can now work to improve drug discovery and personalized medicine. The discovery started out with an entirely different goal. Over the past few years, […]

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Scientists can now manipulate brain cells using smartphone — ScienceDaily

A team of scientists in Korea and the United States have invented a device that can control neural circuits using a tiny brain implant controlled by a smartphone. Researchers, publishing in Nature Biomedical Engineering, believe the device can speed up efforts to uncover brain diseases such as Parkinson’s, Alzheimer’s, addiction, depression, and pain. The device, using […]

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Scientists have developed a method to test whether an infection is resistant to common antibiotics — ScienceDaily

Scientists have developed a method to test whether an infection is resistant to common antibiotics. Beta-lactam antibiotics (such as penicillin) are one of the most important classes of antibiotics, but resistance to them has grown to such an extent that doctors often avoid prescribing them in favour of stronger drugs. Scientists from the University of […]

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E. coli superbug strains can persist in healthy women’s guts — ScienceDaily

A recent study of over 1,000 healthy women with no symptoms of urinary tract infections showed nearly 9 percent carried multi-drug resistant Escherichia coli strains in their guts. This is of clinical concern because disease-causing E. coli bacteria can transfer from the digestive tract to the female urinary tract via the urethra, the urine duct, which is […]

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